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KMID : 0604520150410020173
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Journal of the Society of Cosmetic Scientists of Korea
2015 Volume.41 No. 2 p.173 ~ p.180
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Antioxidant and Tyrosinase Inhibitory Effects of the Extract Mixtures of Perilla frutescens, Houttuynia cordata and Camellia sinensis
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Lee Kyung-Eun
Lee Eun-Sun
Kang Sang-Gu
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Abstract
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In the present study, antioxidant activities and tyrosinase inhibition of Perilla frutescens, Houttuynia cordata and Camellia sinensis extracts and the extract mixtures (PHC) were investigated. PHC showed 80.2% and 98.0% of free radical scavenging activity in DPPH and ABTS analysis, respectively, and 50% tyrosinase inhibition in 1000 μg/mL concentration. HaCaT cells did not show cell toxicity in 100 μg/mL of the PHC. Furthermore, HaCaT cell viability by co-culture with extract H. cordata was increased more than 10% compared with untreated cells. However, the cell viability was decreased in 500 μg/mL of the extract C. sinensis and the PHC. These results suggested that about 100 μg/mL concentration of the PHC showed proper tyrosinase inhibitory effect and antioxidant activities. The PHC could be used as multifunctional cosmeceutical agents.
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KEYWORD
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anti-oxidant, DPPH, ABTS, tyrosinase inhibition, cell viability
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